The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Alzheimer disease amyloid associated protein
Alzheimer disease amyloid-associated protein
Collagen alpha 1 XXV chain
Collagen alpha 1(XXV) chain
Collagen like Alzheimer amyloid plaque component
Collagen like Alzheimer amyloid plaque component precursor
Collagen type XXV alpha 1
Collagen-like Alzheimer amyloid plaque component
Collagenous Alzheimer amyloid plaque component
Inhibits fibrillization of beta amyloid peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resistant aggregates. Binds heparin.
Expressed predominantly in brain. Deposited preferentially in primitive or neuritic amyloid plaques which are typical of Alzheimer disease.
Contains 7 collagen-like domains.
Undergoes proteolytic cleavage by furin protease to yield the soluble collagen-like Alzheimer amyloid plaque component. Glycosylated. Hydroxylated on 11% of proline residues and 49% of lysine residues.
Membrane. After proteolytic cleavage, CLAC is secreted.