Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSRANCHQE PSVCLQAACP ESWIGFQRKC FYFSDDTKNW TSSQRFCDSQ DADLAQVESF QELNFLLRYK GPSDHWIGLS REQGQPWKWI NGTEWTRQFP ILGAGECAYL NDKGASSARH YTERKWICSK SDIHV
    • Molecular weight

      18 kDa including tags
    • Amino acids

      60 to 191
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab140047 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 85 % SDS-PAGE.

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • C type lectin related f
    • C type lectin superfamily 2, member D
    • C-type lectin domain family 2 member D
    • CLAX
    • CLC2D_HUMAN
    • CLEC2D
    • CLEC2D protein
    • Clec2d5
    • L LT1
    • Lectin like NK cell receptor
    • Lectin like transcript 1
    • Lectin-like NK cell receptor
    • Lectin-like transcript 1
    • LLT-1
    • LLT1
    • OCIL
    • Osteoclast inhibitory lectin
    see all
  • Function

    Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.
  • Tissue specificity

    Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T and B lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells.
  • Sequence similarities

    Contains 1 C-type lectin domain.
  • Cellular localization

    Endoplasmic reticulum and Cell membrane. Cell surface.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab140047 (3µg).

References

ab140047 has not yet been referenced specifically in any publications.

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