Overview

  • Product name
    Recombinant Human CNOT4 protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      LCPACRKPYPEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLA SVRVVQKNLVFVVGLSQRLADPEVLKRPEYFGKFGKIHKVVINNSTSYA
    • Amino acids
      52 to 150
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab159008 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • CCR4 NOT transcription complex subunit 4
    • CCR4-associated factor 4
    • CCR4-NOT transcription complex subunit 4
    • CLONE243
    • CNOT 4
    • Cnot4
    • CNOT4_HUMAN
    • E3 ubiquitin-protein ligase CNOT4
    • NOT 4
    • NOT4
    • NOT4 (negative regulator of transcription 4 yeast) homolog
    • NOT4H
    • Potential transcriptional repressor NOT4Hp
    see all
  • Function
    Has E3 ubiquitin ligase activity. The CCR4-NOT complex functions as general transcription regulation complex.
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Contains 1 C3H1-type zinc finger.
    Contains 1 RING-type zinc finger.
    Contains 1 RRM (RNA recognition motif) domain.
  • Post-translational
    modifications
    Autoubiquitinated.
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

Images

  • ab159008 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab159008 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab159008.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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