The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Collagen alpha-1(XXIX) chain
Collagen alpha-5(VI) chain
Collagen, type VI, alpha 5
Collagen, type XXIX, alpha-1
von Willebrand factor A domain-containing protein 4
Collagen VI acts as a cell-binding protein.
Expressed in skin, followed by lung, small intestine, colon and testis. In skin, it is expressed in the epidermis with strongest staining in suprabasal viable layers. In ATOD patients, it is absent in the most differentiated upper spinous and granular layers (at protein level).
Involvement in disease
Note=Patients affected by atopic dermatitis display an abnormal distribution of COL29A1 mRNA and protein in skin suggesting that COL29A1 may be involved in the pathogenesis of the disease.
Belongs to the type VI collagen family. Contains 10 VWFA domains.
Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
Secreted > extracellular space > extracellular matrix. Deposed in the extracellular matrix of skeletal muscle.