Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: ELISA, WB
Product nameRecombinant Human Corin protein
Expression systemWheat germ
Protein lengthProtein fragment
Amino acids616 to 715
TagsGST tag N-Terminus
Our Abpromise guarantee covers the use of ab153116 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
- activated protease fragment
- ATC 2
FunctionSerine-type endopeptidase involved in atrial natriuretic peptide hormone processing. Converts through proteolytic cleavage the non-functional propeptide NPPA/ANP into the active hormone which promotes natriuresis, diuresis, and vasodilatation. May also process pro-NPPB the B-type natriuretic peptide.
Tissue specificityHighly expressed in heart. Expressed in heart myocytes.
Sequence similaritiesBelongs to the peptidase S1 family.
Contains 2 FZ (frizzled) domains.
Contains 7 LDL-receptor class A domains.
Contains 1 peptidase S1 domain.
Contains 1 SRCR domain.
modificationsN-glycosylated; required for processing and activation.
Activated through proteolytic processing by a trypsin-like protease; cleaved into a N-terminal propeptide and an activated corin protease fragment.
A disulfide bond links the N-terminal propeptide and the activated corin protease fragment.
Cellular localizationCell membrane.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab153116 has not yet been referenced specifically in any publications.