Product nameRecombinant human COX1 / Cyclooxygenase 1 protein
See all COX1 / Cyclooxygenase 1 proteins and peptides
Protein lengthFull length protein
SourceBaculovirus infected Sf9 cells
Amino Acid Sequence
SequenceMSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFG LDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWE FVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRI LPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFF AQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGK LKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQ LSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQE YSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDV IRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDAL EFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFG GEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTELD YKDDDDKHHHHHH
Molecular weight71 kDa including tags
Amino acids1 to 599
TagsHis-DDDDK tag C-Terminus
Additional sequence informationNM_000962.
- Anti-COX1 / Cyclooxygenase 1 antibody [EPR5866] (ab109025)
- Anti-DDDDK tag antibody (ab1162)
- Anti-DDDDK tag antibody - (Equivalent to FLAG antibodies from Sigma) (ab1257)
- Anti-COX1 / Cyclooxygenase 1 antibody [EPR5867] (ab133319)
- Anti-6X His tag® antibody [HIS.H8] (ab18184)
- Anti-DDDDK tag antibody [F-tag-01] - (Equivalent to FLAG antibodies from Sigma) (ab18230)
- Anti-6X His tag® antibody [4D11] (ab5000)
- Anti-6X His tag® antibody (ab9108)
Our Abpromise guarantee covers the use of ab198643 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Mixed various concentrations of enzyme in Assay buffer (100 mM Tris-HCl pH 8, 3 µM EDTA) with 5 µM Hematin for 10 min
then added 100 µM Ampliflu Red and 200 μM arachidonic acid. Fluorescence (ex. 535 em. 590) was measured after 5
minutes at room temperature. Reaction volume was 100 μl. Application: Useful for the study of enzyme kinetics, screening inhibitors and selectivity profiling.
Purity>= 90 % SDS-PAGE.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 0.63% Tris HCl, 0.64% Sodium chloride, 0.02% Potassium chloride, 0.04% Tween, 20% Glycerol, 0.08% Triton-X-100, 0.0067% Diethyldithiocarbamate
Contains 80 µg/ml DDDDK peptide.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- COX 1
- COX 3
FunctionMay play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.
PathwayLipid metabolism; prostaglandin biosynthesis.
Sequence similaritiesBelongs to the prostaglandin G/H synthase family.
Contains 1 EGF-like domain.
Cellular localizationMicrosome membrane. Endoplasmic reticulum membrane.
- Information by UniProt
4-20% SDS-PAGE analysis of 1.2 µg ab198643 with Coomassie staining.
Mixed various concentrations of enzyme in Assay buffer (100 mM Tris-HCl pH 8, 3 µM EDTA) with 5 µM Hematin for 10 min then added 100 µM Ampliflu Red and 200 μM arachidonic acid. Fluorescence (ex. 535 em. 590) was measured after 5 minutes at room temperature. Reaction volume was 100 μl.
ab198643 has not yet been referenced specifically in any publications.