Recombinant Human COXIV Isoform 2 protein (ab164643)

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Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MLPRAAWSLVLRKGGGGRRGMHSSEGTTRGGGKMSPYTNCYAQRYYPMPE EPFCTELNAEEQALKEKEKGSWTQLTHAEKVALYRLQFNETFAEMNRRSN EWKTVMGCVFFFIGFAALVIWWQRVYVFPPKPITLTDERKAQQLQRMLDM KVNPVQGLASRWDYEKKQWKK
    • Amino acids
      1 to 171
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab164643 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • COX IV-2
    • COX4
    • COX4 2
    • COX42_HUMAN
    • COX4B
    • Cox4i2
    • COX4L2
    • COXIV 2
    • Cytochrome c oxidase subunit 4 isoform 2
    • Cytochrome c oxidase subunit 4 isoform 2 mitochondrial [Precursor]
    • Cytochrome c oxidase subunit IV isoform 2
    • cytochrome c oxidase subunit IV isoform 2 (lung)
    • dJ857M17.2
    • mitochondrial
    • RP23 106A3.3
    see all
  • Function
    This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
  • Tissue specificity
    Highly expressed in lung.
  • Involvement in disease
    Defects in COX4I2 are the cause of exocrine pancreatic insufficiency dyserythropoietic anemia and calvarial hyperostosis (EPIDACH) [MIM:612714]. Patients present with pancreatic insufficiency, intestinal malabsorption, failure to thrive, and anemia soon after birth.
  • Sequence similarities
    Belongs to the cytochrome c oxidase IV family.
  • Cellular localization
    Mitochondrion inner membrane.
  • Information by UniProt

Images

  • ab164643 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab164643 has not yet been referenced specifically in any publications.

Publishing research using ab164643? Please let us know so that we can cite the reference in this datasheet.

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