Recombinant Human COXIV Isoform 2 protein (ab164643)
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- References
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Overview
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Product nameRecombinant Human COXIV Isoform 2 protein
See all COXIV Isoform 2 proteins and peptides -
Protein lengthFull length protein
Description
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NatureRecombinant
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SourceWheat germ
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Amino Acid Sequence
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SpeciesHuman
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SequenceMLPRAAWSLVLRKGGGGRRGMHSSEGTTRGGGKMSPYTNCYAQRYYPMPE EPFCTELNAEEQALKEKEKGSWTQLTHAEKVALYRLQFNETFAEMNRRSN EWKTVMGCVFFFIGFAALVIWWQRVYVFPPKPITLTDERKAQQLQRMLDM KVNPVQGLASRWDYEKKQWKK
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Amino acids1 to 171
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Tagsproprietary tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab164643 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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FormLiquid
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Additional notesProtein concentration is above or equal to 0.05 mg/ml.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- COX IV-2
- COX4
- COX4 2
see all -
FunctionThis protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
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Tissue specificityHighly expressed in lung.
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Involvement in diseaseDefects in COX4I2 are the cause of exocrine pancreatic insufficiency dyserythropoietic anemia and calvarial hyperostosis (EPIDACH) [MIM:612714]. Patients present with pancreatic insufficiency, intestinal malabsorption, failure to thrive, and anemia soon after birth.
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Sequence similaritiesBelongs to the cytochrome c oxidase IV family.
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Cellular localizationMitochondrion inner membrane.
- Information by UniProt
Images
Datasheets and documents
References
ab164643 has not yet been referenced specifically in any publications.