Recombinant Human COXIV Isoform 2 protein (ab164643)

Product name

Recombinant Human COXIV Isoform 2 protein
See all COXIV Isoform 2 proteins and peptides
Protein length

Full length protein

Our Abpromise guarantee covers the use of ab164643 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Alternative names
- COX IV-2
- COX4
- COX4 2
- COX42_HUMAN
- COX4B
- Cox4i2
- COX4L2
- COXIV 2
- Cytochrome c oxidase subunit 4 isoform 2
- Cytochrome c oxidase subunit 4 isoform 2 mitochondrial [Precursor]
- Cytochrome c oxidase subunit IV isoform 2
- cytochrome c oxidase subunit IV isoform 2 (lung)
- dJ857M17.2
- mitochondrial
- RP23 106A3.3
see all
Function

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Tissue specificity

Highly expressed in lung.
Involvement in disease

Defects in COX4I2 are the cause of exocrine pancreatic insufficiency dyserythropoietic anemia and calvarial hyperostosis (EPIDACH) [MIM:612714]. Patients present with pancreatic insufficiency, intestinal malabsorption, failure to thrive, and anemia soon after birth.
Sequence similarities

Belongs to the cytochrome c oxidase IV family.
Cellular localization

Mitochondrion inner membrane.
Target information above from: UniProt accession Q96KJ9 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Human COXIV Isoform 2 protein (ab164643)

ab164643 on a 12.5% SDS-PAGE stained with Coomassie Blue.

ab164643 has not yet been referenced specifically in any publications.

Publishing research using ab164643? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"