Description

  • Product name

    Recombinant Human CPI-17 protein
  • Purity

    > 95 % SDS-PAGE.
    ab75206 is purified by using conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MAAQRLGKRV LSKLQSPSRA RGPGGSPGGL QKRHARVTVK YDRRELQRRL DVEKWIDGRL EELYRGMEAD MPDEINIDEL LELESEEERS RKIQGLLKSC GKPVEDFIQE LLAKLQGLHR QPGLRQPSPS HDGSLSPLQD RARTAHP

Specifications

Our Abpromise guarantee covers the use of ab75206 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.0154% DTT, 0.242% Tris, 0.0584% EDTA, 10% Glycerol

General Info

  • Alternative names

    • 17 kDa PKC-potentiated inhibitory protein of PP1
    • 17-KDa protein
    • 17kDa PKC potentiated inhibitory protein of PP1
    • CPI 17
    • CPI 17 alpha
    • CPI 17alpha
    • CPI-17
    • CPI17
    • CPI17 alpha
    • PKC potentiated inhibitory protein of PP1
    • PKC potentiated inhibitory protein of PP1, 17-KD
    • PP14A_HUMAN
    • PPP1INL
    • Ppp1r14a
    • Protein kinase C-potentiated inhibitor of protein phosphatase 1, 17-KD
    • Protein kinase C-potentiated inhibitor protein of 17 kDa
    • Protein phosphatase 1
    • Protein phosphatase 1 regulatory (inhibitor) subunit 14A
    • Protein phosphatase 1 regulatory subunit 14A
    • Regulatory subunit 14A
    see all
  • Function

    Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
  • Tissue specificity

    Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.
  • Sequence similarities

    Belongs to the PP1 inhibitor family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab75206 at approximately 18kDa. (3µg)

References

ab75206 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab75206.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up