Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MSIDSLQLGY AEDGHCKGDI NPNIPYPTRL QWDIPGECQE VIETSLNTAN LLANDVDFHS FPFVAFGKGIIKKCRTSPDA FVQLALQLAH YKDMGKFCLT YEASMTRLFR EGRTETVRSC TTESCDFVRA MVDPAQTVEQRLKLFKLASE KHQHMYRLAM TGSGIDRHLF CLYVVSKYLA VESPFLKEVL SEPWRLSTSQ TPQQQVELFDLENNPEYVSS GGGFGPVADD GYGVSYILVG ENLINFHISS KFSCPETDSH RFGRHLKEAM TDIITLFGLS SNSKK
    • Molecular weight
      32 kDa
    • Amino acids
      489 to 773
    • Tags
      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab128569 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Purity
    > 80 % SDS-PAGE.

  • Form
    Liquid
  • Additional notes

    Product was previously marketed under the MitoSciences sub-brand.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Constituents: 0.79% Tris HCl, 0.15% EDTA, 50% Glycerol, 0.88% Sodium chloride

General Info

  • Alternative names
    • Carnitine O palmitoyltransferase 1 liver isoform
    • Carnitine O palmitoyltransferase I
    • Carnitine O palmitoyltransferase I liver isoform
    • Carnitine O-palmitoyltransferase 1
    • Carnitine O-palmitoyltransferase I
    • Carnitine palmitoyltransferase 1A
    • Carnitine palmitoyltransferase 1A (liver)
    • Carnitine palmitoyltransferase I
    • Carnitine palmitoyltransferase I liver
    • CPT 1
    • CPT I
    • CPT1
    • CPT1 L
    • CPT1-L
    • Cpt1a
    • CPT1A_HUMAN
    • CPTI
    • CPTI-L
    • L CPT1
    • liver isoform
    see all
  • Tissue specificity
    Strong expression in kidney and heart, and lower in liver and skeletal muscle.
  • Pathway
    Lipid metabolism; fatty acid beta-oxidation.
  • Involvement in disease
    Defects in CPT1A are the cause of carnitine palmitoyltransferase 1A deficiency (CPT1AD) [MIM:255120]; also known as CPT-I deficiency or CPT1A deficiency. CPT1AD is a rare autosomal recessive metabolic disorder of long-chain fatty acid oxidation characterized by severe episodes of hypoketotic hypoglycemia usually occurring after fasting or illness. Onset is in infancy or early childhood.
  • Sequence similarities
    Belongs to the carnitine/choline acetyltransferase family.
  • Cellular localization
    Mitochondrion outer membrane.
  • Information by UniProt

Images

  • All lanes : Anti-CPT1A antibody (ab128569) at 1 ug/mL

    Lane 1 : Marker

    Lane 2 : Partial Human Recombinant CPT1A protein 1 ng

    Lane 3 : Partial Human Recombinant CPT1A protein 10 ng

    Secondary

    Goat polyclonal to Mouse IgG – H&L – Pre-Adsorbed (HRP) at 1:10000

    Predicted band size : 32 kDa

    Observed band size : 32 kDa

  • Lane 1 : Marker
    Lane 2 : Partial Human Recombinant CPT1A protein 1 µg

    Gel
    10-20% acrylamide separation gel
    Predicted band size : 32 kDa
    Observed band size : 32 kDa

References

ab128569 has not yet been referenced specifically in any publications.

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