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    recombinant-human-crcp-protein-ab111636.pdf

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Recombinant Human CRCP protein (ab111636)

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SDS-PAGE - Recombinant Human CRCP protein (ab111636)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 95% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: MS, SDS-PAGE

    Description

    • Product name

      Recombinant Human CRCP protein
    • Purity

      > 95 % SDS-PAGE.
      qb111636 was purified using conventional chromatography techniques.
    • Expression system

      Escherichia coli
    • Accession

      O75575
    • Protein length

      Full length protein
    • Animal free

      No
    • Nature

      Recombinant
      • Species

        Human
      • Sequence

        MGSSHHHHHHSSGLVPRGSHMEVKDANSALLSNYEVFQLLTDLKEQRKES GKNKHSSGQQNLNTITYETLKYISKTPCRHQSPEIVREFLTALKSHKLTK AEKLQLLNHRPVTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAEPEA EQKKNTNSNVAMDEEDPA
      • Predicted molecular weight

        19 kDa including tags
      • Amino acids

        1 to 148
      • Tags

        His tag N-Terminus

    Associated products

    • Related Products

      • Anti-6X His tag® antibody [HIS.H8] (ab18184)
      • Anti-6X His tag® antibody [4D11] (ab5000)

    Specifications

    Our Abpromise guarantee covers the use of ab111636 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Mass Spectrometry

      SDS-PAGE

    • Mass spectrometry

      MALDI-TOF
    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol (glycerin, glycerine), 0.58% Sodium chloride

    General Info

    • Alternative names

      • Calcitonin gene related peptide receptor component
      • Calcitonin gene related peptide receptor component protein
      • Calcitonin gene-related peptide-receptor component protein
      • CGRP receptor component protein
      • CGRP-RCP
      • CGRP-receptor component protein
      • CGRPRCP
      • CRCP
      • DNA-directed RNA polymerase III subunit RPC9
      • HsC17
      • RCP
      • RCP9
      • RNA polymerase III subunit C9
      • RPC9_HUMAN
      see all
    • Function

      DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway.
      Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.
    • Tissue specificity

      Ubiquitous. Most prevalent in testis.
    • Sequence similarities

      Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
    • Cellular localization

      Nucleus. Cell membrane.
    • Target information above from: UniProt accession O75575 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human CRCP protein (ab111636)
      SDS-PAGE - Recombinant Human CRCP protein (ab111636)
      15% SDS-PAGE showing ab111636 at approximately 19.0kDa (3µg).

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab111636? Please let us know so that we can cite the reference in this datasheet.

    ab111636 has not yet been referenced specifically in any publications.

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