Recombinant Human CRMP4 protein (ab132289)

Submit a review Submit a question
SDS-PAGE - Recombinant Human CRMP4 protein (ab132289)

    Key features and details

    • Expression system: Wheat germ
    • Suitable for: SDS-PAGE, ELISA, WB

    Description

    • Product name

      Recombinant Human CRMP4 protein

    • Expression system

      Wheat germ

    • Accession

      Q14195

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLI VPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGG TTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQ EVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAE NGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPL YVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAA FVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTA IPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGR ISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQG KIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYD GPVFDLTTTPKGGTPAGSARGSPTRPNPPVRNLHQSGFSLSGTQVDEGVR SASKRIVAPPGGRSNITSLS

      • Predicted molecular weight

        88 kDa including tags

      • Amino acids

        1 to 570

    Specifications

    Our Abpromise guarantee covers the use of ab132289 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      ELISA

      Western blot

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • Collapsin response mediator protein 4
      • Collapsin response mediator protein 4 long
      • CRMP 4
      • CRMP-4
      • CRMP4
      • Dihydropyrimidinase like 3
      • Dihydropyrimidinase related protein 3
      • Dihydropyrimidinase-related protein 3
      • DPYL3_HUMAN
      • DPYSL3
      • DRP 3
      • DRP-3
      • DRP3
      • LCRMP
      • TUC4
      • ULIP
      • ULIP 1
      • ULIP-1
      • ULIP1
      • Unc 33 like phosphoprotein
      • UNc 33 like phosphoprotein 1
      • Unc-33-like phosphoprotein 1
      see all

    • Function

      Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.

    • Tissue specificity

      Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.

    • Sequence similarities

      Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.

    • Post-translational
      modifications

      Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3.

    • Cellular localization

      Cytoplasm. Cell projection > growth cone. Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human CRMP4 protein (ab132289)
      SDS-PAGE - Recombinant Human CRMP4 protein (ab132289)
      12.5% SDS-PAGE stained with Coomassie Blue showing ab132289.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab132289? Please let us know so that we can cite the reference in this datasheet.

    ab132289 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab132289.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com