Description

  • Product name

    Recombinant human CSNK2A1 protein
    See all CSNK2A1 proteins and peptides
  • Purity

    > 95 % SDS-PAGE.
    Purity: >95% as determined by densitometry.
  • Expression system

    Baculovirus infected Sf9 cells
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab60763 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    ab91092 (Cow CSNK2A1 full length protein) can be utilized as a substrate for assessing Kinase activity

     This product was previously labelled as CKII alpha

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • Casein kinase 2 alpha 1 polypeptide
    • Casein kinase II alpha 1
    • Casein kinase II alpha 1 subunit
    • Casein kinase II alpha subunit
    • Casein kinase II subunit alpha
    • CK II
    • CK II alpha
    • CK2 alpha
    • CK2 catalytic subunit alpha
    • CK2A1
    • CKII
    • CKIIalpha
    • CSK21_HUMAN
    • CSNK2A1
    see all
  • Function

    Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.
  • Sequence similarities

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.
    Contains 1 protein kinase domain.
  • Information by UniProt

Images

  • The specific activity of CSNK2A1 (ab60763) was determined to be 91 nmol/min/mg as per activity assay protocol
  • SDS PAGE analysis of ab60763
  • Sample Kinase Activity Plot.
  • ab60763 on SDS-PAGE, MW ~70kDa.

References

ab60763 has not yet been referenced specifically in any publications.

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