Description

  • Product name

    Recombinant Human CSP-C protein (His tag)
    See all CSP-C proteins and peptides
  • Purity

    > 90 % SDS-PAGE.
    ab219218 was purified using conventional chromatography techniques.
  • Endotoxin level

    < 1.000 Eu/µg
  • Expression system

    Baculovirus infected insect cells
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      26 kDa
    • Amino acids

      19 to 246
    • Tags

      His tag C-Terminus
    • Additional sequence information

      This product is for the mature full length protein. The signal peptide is not included. (NP_219491)

Specifications

Our Abpromise guarantee covers the use of ab219218 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    Previously labelled as Granzyme H.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 90% PBS, 10% Glycerol

General Info

  • Alternative names

    • Cathepsin G like 2
    • Cathepsin G-like 2
    • CCP X
    • CCP-X
    • CGL 2
    • CGL2
    • CSP C
    • CSP-C
    • CTLA1
    • CTSGL2
    • Cytotoxic serine protease C
    • Cytotoxic T lymphocyte associated serine esterase 1
    • Cytotoxic T lymphocyte proteinase
    • Cytotoxic T-lymphocyte proteinase
    • EC 3.4.21.-
    • GRAH_HUMAN
    • Granzyme H
    • Granzyme H (cathepsin G-like 2, protein h-CCPX)
    • GZMH
    • Protein h CCPX
    see all
  • Function

    Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.
  • Tissue specificity

    Constituvely expressed in NK cells.
  • Sequence similarities

    Belongs to the peptidase S1 family. Granzyme subfamily.
    Contains 1 peptidase S1 domain.
  • Cellular localization

    Cytoplasmic granule. Cytoplasmic granules of cytolytic T-lymphocytes.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab219218 (3μg).

    Molecular weight: 28-40kDa (SDS-PAGE under reducing conditions).

References

ab219218 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab219218.
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