Description

  • Product name

    Recombinant human CXCL11 protein
    See all CXCL11 proteins and peptides
  • Biological activity

     Activity verified by intracellular calcium flux using commercially available CXCR3 expressing cells.

  • Purity

    > 95 % SDS-PAGE.
    Expressed in E. coli then processed, refolded and purified to yield the native, secreted form of the mature chemokine. >98% pure by SDS-PAGE, HPLC, MALDI-MS and NMR analysis.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      8 kDa
    • Amino acids

      22 to 94
    • Additional sequence information

      Full-length mature protein lacking the signal sequence.

Specifications

Our Abpromise guarantee covers the use of ab229837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

    Other

    Mass Spectrometry

    HPLC

  • Mass spectrometry

    MALDI-TOF
  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C long term.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Add deionized water to desired volume, aliquot and freeze unused portion.

General Info

  • Alternative names

    • b R1
    • b-R1
    • Beta-R1
    • betaR1
    • C-X-C motif chemokine 11
    • Chemokine (C-X-C motif) ligand 11
    • Chemokine C-X-C motif ligand 11
    • CXC11
    • CXCL11
    • CXL11_HUMAN
    • H174
    • I TAC
    • I-TAC
    • Interferon gamma inducible protein 9
    • Interferon gamma-inducible protein 9
    • Interferon inducible T cell alpha chemoattractant
    • Interferon-inducible T-cell a chemoattractant I-TAC
    • Interferon-inducible T-cell alpha chemoattractant
    • IP 9
    • IP-9
    • IP9
    • ITAC
    • MGC102770
    • SCYB11
    • SCYB9B
    • Small inducible cytokine B11
    • Small inducible cytokine subfamily B (Cys-X-Cys) member 11
    • Small inducible cytokine subfamily B (Cys-X-Cys) member 9B
    • Small inducible cytokine subfamily B, member 11
    • Small inducible cytokine subfamily B, member 9B
    • Small-inducible cytokine B11
    see all
  • Function

    Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
  • Tissue specificity

    High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.
  • Sequence similarities

    Belongs to the intercrine alpha (chemokine CxC) family.
  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • ab229837 activity verified by intracellular calcium flux using commercially available CXCR3 expressing cells.

References

ab229837 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab229837.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up