Product nameRecombinant Human CXCL7/PBP protein
See all CXCL7/PBP proteins and peptides
Protein lengthFull length protein
Amino Acid Sequence
SequenceRecombinant Human NAP-2 is a 7.6 kDa protein containing 70 amino acid residues: AELRCMCIKT TSGIHPKNIQ SLEVIGKGTH CNQVEVIATL KD GRKICLDP DAPRIKKIVQKKLAGDESAD
Our Abpromise guarantee covers the use of ab9556 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Endotoxin level< 0.100 Eu/µg
Previously labelled as CXCL7.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
ReconstitutionFor lot specific reconstitution information please contact our Scientific Support Team.
- B TG1
- Beta TG
- Beta thromboglobulin
FunctionLA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.
Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
modificationsProteolytic removal of residues 1-9 produces the active peptide connective tissue-activating peptide III (CTAP-III) (low-affinity platelet factor IV (LA-PF4)).
Proteolytic removal of residues 1-13 produces the active peptide beta-thromboglobulin, which is released from platelets along with platelet factor 4 and platelet-derived growth factor.
NAP-2(1-66) is produced by proteolytical processing, probably after secretion by leukocytes other than neutrophils.
NAP-2(73) and NAP-2(74) seem not be produced by proteolytical processing of secreted precursors but are released in an active form from platelets.
- Information by UniProt
Recombinant Human CXCL7/PBP protein (ab9556) at 1/1000 dilution + Human CXCL7 active recombinant protein, 10 ng
Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/100000 dilution
Observed band size: 11 kDa why is the actual band size different from the predicted?
Exposure time: 5 seconds
Blocking and Diluting buffer - 5% NFDM/TBST
ab9556 has not yet been referenced specifically in any publications.