Overview

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFEDRN AFVTGIARYIEQATVHSSMNEMLEEGHEYAVMLYTWRSCSRAIPQVKCNE QPNRVEIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCSEVKRLCHAERRK DFVSEAYLLTLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMAD PQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLADIVNICVDYYE NKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFK QLQVVPLFGDMQIELARYIKTSAHYEENKSKWTCTQSSISPQYNICEQMV QIRDDHIRFISELARYSNSEVVTGSGLDSQKSDEEYRELFDLALRGLQLL SKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEEKFAF VEVIAMIKGLQVLMGRMESVFNQAIRNTIYAALQDFAQVTLREPLRQAVR KKKNVLISVLQAIRKTICDWEGGREPPNDPCLRGEKDPKGGFDIKVPRRA VGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLDGPIVLAIEDFHKQSFF FTHLLNISEALQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDH ILETKEPSMMEYVLYPLDLYNDSAYYALTKFKKQFLYDEIEAEVNLCFDQ FVYKLADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYPPSNRYETLLK QRHVQLLGRSIDLNRLITQRTSAAMYKSLDQAISRFESEDLTSIVELEWL LEINRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGRITLHVFWELNFDF LPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSHI YSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKT LIEVMPKICRLPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQSLREVG NAILFCLLIEQALSQEEVCDLLHAAPFQNILPRVYIKEGERLEVRMKRLE AKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIR SYLQDPIWRGPPPTNGVMHVDECVEFHRLWSAMQFVYCIPVGTNEFTAEQ CFGDGLNWAGCSIIVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPL KKMADRIRKYQILNNEVFAILNKYMKSVETDSSTVEHVRCFQPPIHQSLA TTC
    • Molecular weight

      163 kDa including tags
    • Amino acids

      1 to 1253

Specifications

Our Abpromise guarantee covers the use of ab132835 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • CYFP2
    • cytoplasmic FMR1 interacting protein 2
    • KIAA1168
    • p53 inducible protein
    • p53-inducible protein 121
    • PIR121
    see all
  • Relevance

    CYFIP2 is involved in T cell adhesion and p53 dependent induction of apoptosis. It does not bind RNA but is up regulated significantly in CD4+ T lymphocytes from patients with multiple sclerosis. There are 2 isoforms produced by alternative splicing.
  • Cellular localization

    Cytoplasm perinuclear region. Cell junction, synapse, synaptosome. Treatment with leptomycin-B triggers translocation to the nucleus.

Images

  • 12.5% SDS-PAGE analysis of ab132835 stained with Coomassie Blue.

References

ab132835 has not yet been referenced specifically in any publications.

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