Recombinant Human CYP2A6 protein (ab114776)
- Datasheet
- References
- Protocols
Description
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Product name
Recombinant Human CYP2A6 protein -
Expression system
Wheat germ -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
LGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGL ARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGFATIPRNYTMSFLPR -
Predicted molecular weight
37 kDa including tags -
Amino acids
395 to 494
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Specifications
Our Abpromise guarantee covers the use of ab114776 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
ELISA
Western blot
SDS-PAGE
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Form
Liquid -
Additional notes
Protein concentration is above or equal to 0.05 mg/ml.
Best used within three months from the date of receipt.This product was previously labelled as Cytochrome P450 2A6
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.3% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- Coumarin 7 hydroxylase
- Coumarin 7-hydroxylase
- CP2A6_HUMAN
see all -
Function
Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Possesses low phenacetin O-deethylation activity. -
Tissue specificity
Liver. -
Sequence similarities
Belongs to the cytochrome P450 family. -
Cellular localization
Endoplasmic reticulum membrane. Microsome membrane. - Information by UniProt
Images
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SDS-PAGE - Recombinant Human CYP2A6 protein (ab114776)ab114776 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.
Datasheets and documents
References
ab114776 has not yet been referenced specifically in any publications.
