Description

  • Product name

    Recombinant Human CYP2D6 protein
  • Biological activity

    ab73434 reacts with autoimmune hepatitis patient sera.
  • Expression system

    Baculovirus infected Sf9 cells
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      56 kDa
    • Additional sequence information

      Cytochrome P450 2D6 Human Recombinant (also called liver/kidney microsomal antigen 1) produced in SF9, is a glycosylated, polypeptide chain having a molecular mass of 55,801 Dalton.

Specifications

Our Abpromise guarantee covers the use of ab73434 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes


    This protein is suitable for biotinylation and iodination.

    ab73434 reacts with autoimmune hepatitis patient sera.

     This product was previously labelled as Cytochrome P450 2D6

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 7.60
    Constituents: 0.0006% Potassium chloride, 0.2624% Sodium phosphate, 20% Glycerol, 2.32% Sodium chloride

General Info

  • Alternative names

    • Cholesterol 25-hydroxylase
    • CP2D6_HUMAN
    • CPD6
    • CYP2D
    • CYP2D6
    • CYP2D7AP
    • CYP2D7BP
    • CYP2D7P2
    • CYP2D8P2
    • CYP2DL1
    • CYPIID6
    • Cytochrome P450 2D6
    • Cytochrome P450 DB1
    • Cytochrome P450 family 2 subfamily D member 6
    • Cytochrome P450 family 2 subfamily D polypeptide 6
    • Cytochrome P450-DB1
    • Debrisoquine 4 hydroxylase
    • Debrisoquine 4-hydroxylase
    • Flavoprotein linked monooxygenase
    • Microsomal monooxygenase
    • P450 DB1
    • P450C2D
    • P450DB1
    • Xenobiotic monooxygenase
    see all
  • Function

    Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.
  • Sequence similarities

    Belongs to the cytochrome P450 family.
  • Cellular localization

    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt

References

ab73434 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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