Recombinant Human CYP51A1 protein (ab158260)
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Overview
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Product nameRecombinant Human CYP51A1 protein
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Protein lengthProtein fragment
Description
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NatureRecombinant
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SourceWheat germ
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Amino Acid Sequence
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SpeciesHuman
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SequenceSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGEN FAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPVIRYKRRSK
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Amino acids410 to 509
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Tagsproprietary tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab158260 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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FormLiquid
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Additional notesProtein concentration is above or equal to 0.05 mg/ml.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- CP51
- CP51A_HUMAN
- CYP51
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FunctionCatalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
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Tissue specificityUbiquitously expressed with highest levels in testis, ovary, adrenal, prostate, liver, kidney and lung.
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PathwaySteroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 1/6.
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Sequence similaritiesBelongs to the cytochrome P450 family.
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Cellular localizationEndoplasmic reticulum membrane. Microsome membrane.
- Information by UniProt
Images
Datasheets and documents
References
ab158260 has not yet been referenced specifically in any publications.