Recombinant Human CYP51A1 protein (ab158260)

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Overview

  • Product name
    Recombinant Human CYP51A1 protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      SPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGEN FAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPVIRYKRRSK
    • Amino acids
      410 to 509
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab158260 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • CP51
    • CP51A_HUMAN
    • CYP51
    • CYP51A1
    • CYPL1
    • CYPLI
    • Cytochrome P450 51
    • Cytochrome P450 51A1
    • Cytochrome P450 family 51 subfamily A member 1
    • Cytochrome P450 family 51 subfamily A polypeptide 1
    • Cytochrome P450, 51 (lanosterol 14 alpha demethylase)
    • Cytochrome P450-14DM
    • Cytochrome P45014DM
    • Cytochrome P450LI
    • Lanosterol 14-alpha demethylase
    • LDM
    • P450 14DM
    • P450L1
    • Sterol 14-alpha demethylase
    see all
  • Function
    Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
  • Tissue specificity
    Ubiquitously expressed with highest levels in testis, ovary, adrenal, prostate, liver, kidney and lung.
  • Pathway
    Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 1/6.
  • Sequence similarities
    Belongs to the cytochrome P450 family.
  • Cellular localization
    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt

Images

  • ab158260 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab158260 has not yet been referenced specifically in any publications.

Publishing research using ab158260? Please let us know so that we can cite the reference in this datasheet.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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