Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Expressed in liver, lung and heart right ventricle.
Belongs to the cytochrome P450 family.
Phosphorylation is accompanied by a decrease in enzyme activity.