Recombinant Human Cytochrome P450 2E1 protein (His tag) (denatured) (ab202203)

Description

  • Product name

    Recombinant Human Cytochrome P450 2E1 protein (His tag) (denatured)
  • Purity

    > 85 % SDS-PAGE.
    ab202203 was purified using conventional chromatography.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSSWNLPPG PFPLPIIGNL FQLELKNIPK SFTRLAQRFG PVFTLYVGSQ RMVVMHGYKA VKEALLDYKD EFSGRGDLPA FHAHRDRGII FNNGPTWKDI RRFSLTTLRN YGMGKQGNES RIQREAHFLL EALRKTQGQP FDPTFLIGCA PCNVIADILF RKHFDYNDEK FLRLMYLFNE NFHLLSTPWL QLYNNFPSFL HYLPGSHRKV IKNVAEVKEY VSERVKEHHQ SLDPNCPRDL TDCLLVEMEK EKHSAERLYT MDGITVTVAD LFFAGTETTS TTLRYGLLIL MKYPEIEEKL HEEIDRVIGP SRIPAIKDRQ EMPYMDAVVH EIQRFITLVP SNLPHEATRD TIFRGYLIPK GTVVVPTLDS VLYDNQEFPD PEKFKPEHFL NENGKFKYSD YFKPFSTGKR VCAGEGLARM ELFLLLCAIL QHFNLKPLVD PKDIDLSPIH IGFGCIPPRY KLCVIPRS
    • Predicted molecular weight

      56 kDa including tags
    • Amino acids

      29 to 493
    • Tags

      His tag N-Terminus
    • Additional sequence information

      NCBI Accession: NP_000764
  • Description

    Recombinant Human Cytochrome P450 2E1 protein (His tag)

Specifications

Our Abpromise guarantee covers the use of ab202203 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8
    Constituents: 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • 4-nitrophenol 2-hydroxylase
    • CP2E1_HUMAN
    • CPE1
    • CYP2E
    • Cyp2e1
    • CYPIIE1
    • Cytochrome P450 2E1
    • Cytochrome P450 isozyme 3A
    • Cytochrome P450 LM3A
    • Cytochrome P450, family 2, subfamily e, polypeptide 1
    • Cytochrome P450, subfamily IIE
    • cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1
    • Cytochrome P450-ALC
    • Cytochrome P450-J
    • Cytochrome P450RLM6
    • EC 1.14.13.-
    • EC 1.14.13.n7
    • Ethanol-inducible P450
    • Flavoprotein-linked monooxygenase
    • MGC133529
    • Microsomal monooxygenase
    • OTTHUMP00000020813
    • OTTHUMP00000046571
    • P450 ALC
    • P450-J
    • P450C2E
    • P450J
    • P450RLM6
    • Xenobiotic monooxygenase
    see all
  • Function

    Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.
  • Sequence similarities

    Belongs to the cytochrome P450 family.
  • Cellular localization

    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab202203 (3 µg)

References

ab202203 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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