Recombinant Human Cytoplasmic dynein 1 intermediate chain 1 protein (ab158299)

Overview

  • Product name
    Recombinant Human Cytoplasmic dynein 1 intermediate chain 1 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDS DLDRKRRETEALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDL GPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYS KETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELT EEEKQQILHLEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDV QAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVL WDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCS WSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTA CRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLW TTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTE VPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE WTRFARTLVEIRANRADSEEEGTVELSA
    • Amino acids
      1 to 628
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab158299 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Cytoplasmic dynein 1 intermediate chain 1
    • Cytoplasmic dynein intermediate chain 1
    • cytosolic
    • DC1I1_HUMAN
    • DH IC 1
    • DH IC-1
    • DH IC1
    • DNCI1
    • DNCIC1
    • Dync1i1
    • Dynein cytoplasmic 1 intermediate chain 1
    • Dynein intermediate chain 1
    • Dynein intermediate chain 1, cytosolic
    • Dynein, cytoplasmic, intermediate polypeptide 1
    see all
  • Function
    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
  • Sequence similarities
    Belongs to the dynein intermediate chain family.
    Contains 7 WD repeats.
  • Cellular localization
    Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.
  • Information by UniProt

Images

  • ab158299 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab158299 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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