Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLL SNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFS SLKDFVKHFANQPLIGSETGTLMVLKHPYPRKVEEPSIYESVRVHTAMQT GRTEDDLVPTAPSLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQM SPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLCAKTGVEADEW IKILRWKLSQIRKQLNQGEGTIRSRSFIFK
    • Amino acids
      1 to 280
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab162070 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • B cell adapter molecule of 32 kDa
    • B lymphocyte adapter protein Bam32
    • B-cell adapter molecule of 32 kDa
    • BAM32
    • DAPP1
    • DAPP1_HUMAN
    • DKFZp667E0716
    • Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
    • Dual adaptor of phosphotyrosine and 3 phosphoinositides
    • hDAPP1
    see all
  • Function
    May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.
  • Tissue specificity
    Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.
  • Sequence similarities
    Contains 1 PH domain.
    Contains 1 SH2 domain.
  • Post-translational
    modifications
    Phosphorylated on tyrosine residues.
  • Cellular localization
    Cytoplasm. Membrane. Membrane-associated after cell stimulation leading to its translocation.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human DAPP1 protein (ab162070)
    SDS-PAGE - Recombinant Human DAPP1 protein (ab162070)
    ab162070 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab162070 has not yet been referenced specifically in any publications.

Publishing research using ab162070? Please let us know so that we can cite the reference in this datasheet.

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