Recombinant Human DAPP1 protein (ab162070)

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SDS-PAGE - Recombinant Human DAPP1 protein (ab162070)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: WB, ELISA

    Description

    • Product name

      Recombinant Human DAPP1 protein

    • Expression system

      Wheat germ

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLL SNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFS SLKDFVKHFANQPLIGSETGTLMVLKHPYPRKVEEPSIYESVRVHTAMQT GRTEDDLVPTAPSLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQM SPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLCAKTGVEADEW IKILRWKLSQIRKQLNQGEGTIRSRSFIFK

      • Amino acids

        1 to 280

      • Tags

        GST tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab162070 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Western blot

      ELISA

    • Form

      Liquid

    • Additional notes

       

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • B cell adapter molecule of 32 kDa
      • B lymphocyte adapter protein Bam32
      • B-cell adapter molecule of 32 kDa
      • BAM32
      • DAPP1
      • DAPP1_HUMAN
      • DKFZp667E0716
      • Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
      • Dual adaptor of phosphotyrosine and 3 phosphoinositides
      • hDAPP1
      see all

    • Function

      May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.

    • Tissue specificity

      Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.

    • Sequence similarities

      Contains 1 PH domain.
      Contains 1 SH2 domain.

    • Post-translational
      modifications

      Phosphorylated on tyrosine residues.

    • Cellular localization

      Cytoplasm. Membrane. Membrane-associated after cell stimulation leading to its translocation.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human DAPP1 protein (ab162070)
      SDS-PAGE - Recombinant Human DAPP1 protein (ab162070)
      ab162070 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab162070? Please let us know so that we can cite the reference in this datasheet.

    ab162070 has not yet been referenced specifically in any publications.

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