Description

  • Product name

    Recombinant Human DCD protein (Tagged)
  • Purity

    > 85 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      YDPEAASAPGSGNPCHEASAAQKENAGEDPGLARQAPKPRKQRSSLLEKG LDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL
    • Predicted molecular weight

      23 kDa including tags
    • Amino acids

      20 to 110
    • Tags

      His tag N-Terminus
    • Additional sequence information

      This product is the mature full length protein from aa 20 to 110. The signal peptide is not included. N-terminal 6xHis-B2M-tag.

Specifications

Our Abpromise guarantee covers the use of ab235679 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    Protein previously labeled as Dermcidin.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C long term. Avoid freeze / thaw cycle.

    Constituents: Tris buffer, 50% Glycerol

General Info

  • Alternative names

    • AIDD
    • dcd
    • DCD 1
    • DCD-1
    • DCD_HUMAN
    • Dermcidin
    • DSEP
    • HCAP
    • PIF
    • Preproteolysin
    see all
  • Function

    DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat.
    Survival-promoting peptide promotes survival of neurons and displays phosphatase activity. It may bind IgG.
  • Tissue specificity

    Specifically and constitutively expressed in eccrine sweat gland cells. Secreted into the sweat at a concentration of 1-10 micrograms/ml.
  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis with 5% enrichment gel and 15% separation gel of ab235679.

References

ab235679 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Functional Studies
This product (Dermcidin) appears to be functionally active in terms of antimicrobial activity.

Abcam user community

Verified customer

Submitted Mar 01 2019

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