The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Decoy receptor 2
Decoy with truncated death domain
TNF receptor related receptor for TRAIL
TNF related apoptosis inducing ligand receptor 4
TNF-related apoptosis-inducing ligand receptor 4
TRAIL receptor 4
TRAIL receptor with a truncated death domain
Tumor necrosis factor receptor superfamily member 10D
Tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart.
Contains 1 death domain. Contains 3 TNFR-Cys repeats.