Recombinant Human DcR3 protein (ab157279)

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Functional Studies - Recombinant Human DcR3 protein (ab157279)

    Key features and details

    • Expression system: HEK 293 cells
    • Purity: > 95% SDS-PAGE
    • Endotoxin level: < 0.100 Eu/µg
    • Suitable for: Functional Studies, SDS-PAGE

    Description

    • Product name

      Recombinant Human DcR3 protein
      See all DcR3 proteins and peptides

    • Biological activity

      ab157279 binds Human LIGHT. Does not bind Human FasL.

    • Purity

      > 95 % SDS-PAGE.

    • Endotoxin level

      < 0.100 Eu/µg

    • Expression system

      HEK 293 cells

    • Accession

      O95407

    • Protein length

      Protein fragment

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MRALEGPGLS LLCLVLALPA LLPVPAVRGV AETPTYPWRD AETGERLVCA QCPPGTFVQR PCRRDSPTTC GPCPPRHYTQ FWNYLERCRY CNVLCGEREE EARACHATHN RACRCRTGFF AHAGFCLEHA SCPPGAGVIA PGTPSQNTQC QPCPPGTFSA SSSSSEQCQP HRNCTALGLA LNVPGSSSHD TLCTSCTGFP LSTRVPGAEE CERAVIDFVA FQDISIKRLQ RLLQALEAPE GWGPTP

      • Predicted molecular weight

        58 kDa including tags

      • Amino acids

        1 to 246

    Specifications

    Our Abpromise guarantee covers the use of ab157279 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Functional Studies

      SDS-PAGE

    • Form

      Lyophilized

    • Additional notes

      ab157279 binds Human LIGHT. Does not bind Human FasL.
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20ºC.

      Constituent: 99% PBS

    • Reconstitution
      Reconstitute with 50µl sterile water to a concentration of 1 mg/ml. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

    General Info

    • Alternative names

      • DcR3
      • Decoy receptor 3
      • Decoy receptor for Fas ligand
      • DJ583P15.1.1
      • M68
      • M68E
      • OTTHUMP00000031583
      • TNF6B_HUMAN
      • TNFRSF6B
      • TR6
      • Tumor necrosis factor receptor superfamily member 6B
      • Tumor necrosis factor receptor superfamily member 6b decoy
      • UNQ186/PRO212
      see all

    • Function

      Decoy receptor for the cytotoxic ligands TNFS14/LIGHT and TNFSF6/FASL. Protects against apoptosis.

    • Tissue specificity

      Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.

    • Sequence similarities

      Contains 4 TNFR-Cys repeats.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    • Functional Studies - Recombinant Human DcR3 protein (ab157279)
      Functional Studies - Recombinant Human DcR3 protein (ab157279)
      ELISA analysis of ab157279.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab157279? Please let us know so that we can cite the reference in this datasheet.

    ab157279 has not yet been referenced specifically in any publications.

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