Recombinant Human DcR3 protein (ab157279)

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Description

  • Product name

    Recombinant Human DcR3 protein
    See all DcR3 proteins and peptides

  • Biological activity

    ab157279 binds Human LIGHT. Does not bind Human FasL.

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

    < 0.100 Eu/µg

  • Expression system

    HEK 293 cells

  • Accession

    O95407

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MRALEGPGLS LLCLVLALPA LLPVPAVRGV AETPTYPWRD AETGERLVCA QCPPGTFVQR PCRRDSPTTC GPCPPRHYTQ FWNYLERCRY CNVLCGEREE EARACHATHN RACRCRTGFF AHAGFCLEHA SCPPGAGVIA PGTPSQNTQC QPCPPGTFSA SSSSSEQCQP HRNCTALGLA LNVPGSSSHD TLCTSCTGFP LSTRVPGAEE CERAVIDFVA FQDISIKRLQ RLLQALEAPE GWGPTP

    • Predicted molecular weight

      58 kDa including tags

    • Amino acids

      1 to 246

Associated products

Specifications

Our Abpromise guarantee covers the use of ab157279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Form

    Lyophilised

  • Additional notes

    ab157279 binds Human LIGHT. Does not bind Human FasL.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituent: 99% PBS

  • Reconstitution
    Reconstitute with 50µl sterile water to a concentration of 1 mg/ml. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

General Info

  • Alternative names

    • DcR3
    • Decoy receptor 3
    • Decoy receptor for Fas ligand
    • DJ583P15.1.1
    • M68
    • M68E
    • OTTHUMP00000031583
    • TNF6B_HUMAN
    • TNFRSF6B
    • TR6
    • Tumor necrosis factor receptor superfamily member 6B
    • Tumor necrosis factor receptor superfamily member 6b decoy
    • UNQ186/PRO212
    see all

  • Function

    Decoy receptor for the cytotoxic ligands TNFS14/LIGHT and TNFSF6/FASL. Protects against apoptosis.

  • Tissue specificity

    Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.

  • Sequence similarities

    Contains 4 TNFR-Cys repeats.

  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • Functional Studies - Recombinant Human DcR3 protein (ab157279)
    Functional Studies - Recombinant Human DcR3 protein (ab157279)
    ELISA analysis of ab157279.

References

ab157279 has not yet been referenced specifically in any publications.

Publishing research using ab157279? Please let us know so that we can cite the reference in this datasheet.

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