Recombinant Human DcR3 protein (ab157279)

Our Abpromise guarantee covers the use of ab157279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Stability and Storage

Shipped at 4°C. Store at -20ºC.

Constituent: 99% PBS
Reconstitution

Reconstitute with 50µl sterile water to a concentration of 1 mg/ml. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Alternative names
- DcR3
- Decoy receptor 3
- Decoy receptor for Fas ligand
- DJ583P15.1.1
- M68
- M68E
- OTTHUMP00000031583
- TNF6B_HUMAN
- TNFRSF6B
- TR6
- Tumor necrosis factor receptor superfamily member 6B
- Tumor necrosis factor receptor superfamily member 6b decoy
- UNQ186/PRO212
see all
Function

Decoy receptor for the cytotoxic ligands TNFS14/LIGHT and TNFSF6/FASL. Protects against apoptosis.
Tissue specificity

Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.
Sequence similarities

Contains 4 TNFR-Cys repeats.
Cellular localization

Secreted.
Target information above from: UniProt accession O95407 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

Functional Studies - Recombinant Human DcR3 protein (ab157279)

ELISA analysis of ab157279.

ab157279 has not yet been referenced specifically in any publications.

Publishing research using ab157279? Please let us know so that we can cite the reference in this datasheet.

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