The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
ATP dependent RNA helicase DDX3Y
ATP-dependent RNA helicase DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 Y linked
DEAD box protein 3
DEAD box protein 3 Y chromosomal
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide Y chromosome
Probable ATP-dependent RNA helicase. May play a role in spermatogenesis.
Testis-specific. Expressed predominantly in spermatogonia.
Involvement in disease
Note=DDX3Y is located in the 'azoospermia factor a' (AZFa) region on chromosome Y which is deleted in Sertoli cell-only syndrome. This is an infertility disorder in which no germ cells are visible in seminiferous tubules leading to azoospermia.
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain.
Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm in an XPO1-dependent manner.