Description

  • Product name

    Recombinant human DEFB-4 protein
    See all DEFB-4 proteins and peptides
  • Biological activity

    Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-100.0 ng/mL.

  • Purity

    > 98 % SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP
    • Predicted molecular weight

      9 kDa
    • Amino acids

      23 to 72
    • Additional sequence information

      Mature form without signal peptide.

Associated products

Specifications

Our Abpromise guarantee covers the use of ab200234 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    HPLC

    SDS-PAGE

    Functional Studies

  • Form

    Lyophilised
  • Additional notes

    Protein previously labeled as beta 4 Defensin.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at 4°C prior to reconstitution. Upon reconsitution add a carrier protein (0.1% BSA). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 99% Phosphate Buffer, 0.75% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL.

General Info

  • Alternative names

    • BD 4
    • BD-4
    • BD4
    • beta 104
    • beta 4 Defensin
    • Beta defensin 4
    • Beta-defensin 104
    • Beta-defensin 4
    • D104A_HUMAN
    • DEFB-4
    • DEFB104B
    • Defensin
    • Defensin beta 104
    • Defensin beta 4 precursor
    • hBD 4
    • hBD-4
    • hBD4
    see all
  • Function

    Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103.
  • Tissue specificity

    High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested.
  • Sequence similarities

    Belongs to the beta-defensin family.
  • Cellular localization

    Secreted.
  • Information by UniProt

References

ab200234 has not yet been referenced specifically in any publications.

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