Description

  • Product name

    Recombinant Human DHPS/DHS protein
    See all DHPS/DHS proteins and peptides
  • Purity

    > 95 % SDS-PAGE.
    ab116440 was purified by proprietary chromatographic techniques and filter sterilized.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MEGSLEREAP AGALAAVLKH SSTLPPESTQ VRGYDFNRGV NYRALLEAFG TTGFQATNFG RAVQQVNAMI EKKLEPLSQD EDQHADLTQS RRPLTSCTIF LGYTSNLISS GIRETIRYLV QHNMVDVLVT TAGGVEEDLI KCLAPTYLGE FSLRGKELRE NGINRIGNLL VPNENYCKFE DWLMPILDQM VMEQNTEGVK WTPSKMIARL GKEINNPESV YYWAQKNHIP VFSPALTDGS LGDMIFFHSY KNPGLVLDIV EDLRLINTQA IFAKCTGMII LGGGVVKHHI ANANLMRNGA DYAVYINTAQ EFDGSDSGAR PDEAVSWGKI RVDAQPVKVY ADASLVFPLL VAETFAQKMD AFMHEKNED
    • Predicted molecular weight

      43 kDa including tags
    • Amino acids

      1 to 369
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab116440 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    ab116440 is stable at 4°C for 30 days, it should be stored desiccated below -20°C for periods greater than 30 days. Please avoid freeze-thaw cycles.

    Protein previously labeled as DHPS.

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride, 20% Glycerol

General Info

  • Alternative names

    • Deoxyhypusine synthase
    • Dhps
    • DHS
    • DHYS_HUMAN
    • DS
    • MIG13
    • Migration inducing gene 13
    see all
  • Function

    Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
  • Pathway

    Protein modification; eIF5A hypusination.
  • Sequence similarities

    Belongs to the deoxyhypusine synthase family.
  • Post-translational
    modifications

    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt

References

ab116440 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab116440.
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