Overview

  • Product name
    Recombinant Human DHRS9 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
      Q9BPW9
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGSHMRKGKL KIEDITDKYI FITGCDSGFG NLAARTFDKK GFHVIAACLT ESGSTALKAE TSERLRTVLL DVTDPENVKR TAQWVKNQVG EKGLWGLINN AGVPGVLAPT DWLTLEDYRE PIEVNLFGLI SVTLNMLPLV KKAQGRVINV SSVGGRLAIV GGGYTPSKYA VEGFNDSLRR DMKAFGVHVS CIEPGLFKTN LADPVKVIEK KLAIWEQLSP DIKQQYGEGY IEKSLDKLKG NKSYVNMDLS PVVECMDHAL TSLFPKTHYA AGKDAKIFWI PLSHMPAALQ DFLLLKQKAE LANPKAV
    • Molecular weight
      36 kDa including tags
    • Amino acids
      18 to 319
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab123162 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 90 % SDS-PAGE.
    ab123162 was purified by using conventional chromatography.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% PMSF, 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

General Info

  • Alternative names
    • 3 alpha hydroxysteroid dehydrogenase
    • 3-@alpha-HSD
    • 3-@alpha-hydroxysteroid dehydrogenase
    • 3-alpha hydroxysteroid dehydrogenase
    • 3-alpha-HSD
    • 3alpha HSD
    • Dehydrogenase/reductase SDR family member 9
    • DHRS9
    • DHRS9_HUMAN
    • NADP dependent retinol dehydrogenase/reductase
    • NADP-dependent retinol dehydrogenase/reductase
    • RDH-E2
    • Rdh15
    • RDHE2
    • RDHL
    • RDHTBE
    • retinol dehydrogenase homolog
    • Retinol dehydrogenase, tracheobronchiol epithelail cell-specific
    • RETSDR8
    • SDR family, member 9
    • SDR9C4
    • short chain dehydrogenase/reductase family 9
    • short chain dehydrogenase/reductase family 9C, member 4
    • Short chain dehydrogenase/reductase retSDR8
    • Short-chain dehydrogenase/reductase retSDR8
    see all
  • Function
    3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. May play a role in the biosynthesis of retinoic acid from retinaldehyde, but seems to have low activity with retinoids. Can utilize both NADH and NADPH.
  • Tissue specificity
    Highly expressed in trachea and epidermis. Detected at lower levels in spinal cord, bone marrow, brain, tongue, esophagus, heart, colon, testis, placenta, lung, skeletal muscle and lymph node.
  • Sequence similarities
    Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Cellular localization
    Microsome membrane. Endoplasmic reticulum membrane. Associated with microsomal membranes.
  • Information by UniProt

Images

  • SDS-PAGE - DHRS9 protein (Tagged-His Tag) (ab123162)
    SDS-PAGE - DHRS9 protein (Tagged-His Tag) (ab123162)
    15% SDS PAGE analysis of 3 µg of Human DHRS9 protein (ab123162).

References

ab123162 has not yet been referenced specifically in any publications.

Publishing research using ab123162? Please let us know so that we can cite the reference in this datasheet.

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