Recombinant Human DHX8/prp22 protein (ab114918)

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Description

  • Product name

    Recombinant Human DHX8/prp22 protein

  • Expression system

    Wheat germ

  • Accession

    Q14562

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      RREGRVANVADVVSKGQRVKVKVLSFTGTKTSLSMKDVDQETGEDLNPNR RRNLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKW

    • Predicted molecular weight

      37 kDa including tags

    • Amino acids

      301 to 400

Associated products

Specifications

Our Abpromise guarantee covers the use of ab114918 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

    ELISA

  • Form

    Liquid

  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.

     This product was previously labelled as DHX8

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • ATP dependent RNA helicase DHX8
    • ATP-dependent RNA helicase dhx8
    • DDX 8
    • DDX8
    • DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8
    • DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8 (RNA helicase)
    • DEAD/H box 8
    • DEAD/H box polypeptide 8
    • DEAH (Asp Glu Ala His) box polypeptide 8
    • DEAH box polypeptide 8
    • DEAH box protein 8
    • DHX 8
    • dhx8
    • DHX8_HUMAN
    • HRH 1
    • HRH1
    • PRP 22
    • PRP22
    • PRP22, S. cerevisiae, homolog of
    • PRPF 22
    • PRPF22
    • RNA helicase HRH 1
    • RNA helicase HRH1
    see all

  • Function

    Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.

  • Sequence similarities

    Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
    Contains 1 S1 motif domain.

  • Domain

    The RS domain confers a nuclear localization signal, and appears to facilitate the interaction with the spliceosome.

  • Cellular localization

    Nucleus.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human DHX8/prp22 protein (ab114918)
    SDS-PAGE - Recombinant Human DHX8/prp22 protein (ab114918)
    12.5% SDS-PAGE showing ab114918 at approximately 36.63kDa.
    Stained with Coomassie Blue.

References

ab114918 has not yet been referenced specifically in any publications.

Publishing research using ab114918? Please let us know so that we can cite the reference in this datasheet.

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