Recombinant Human DLL3 protein (Tagged) (ab226231)

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SDS-PAGE - Recombinant Human DLL3 protein (Tagged) (ab226231)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 90% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE

    Description

    • Product name

      Recombinant Human DLL3 protein (Tagged)
      See all DLL3 proteins and peptides

    • Purity

      > 90 % SDS-PAGE.

    • Expression system

      Escherichia coli

    • Accession

      Q9NYJ7

    • Protein length

      Protein fragment

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        AGVFELQIHSFGPGPGPGAPRSPCSARLPCRLFFRVCLKPGLSEEAAESP CALGAALSARGPVYTEQPGAPAPDLPLPDGLLQVPFRDAWPGTFSFIIET WREELGDQIGGPAWSLLARVAGRRRLAAGGPWARDIQRAGAWELRFSYRA RCEPPAVGTACTRLCRPRSAPSRCGPGLRPCAPLEDECEAPLVCRAGCSP EHGFCEQPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPG PCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGL CVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALR CRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDC RERADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASAL PAAPPGLRPGDPQRYL

      • Predicted molecular weight

        65 kDa including tags

      • Amino acids

        27 to 492

      • Tags

        His tag N-Terminus

      • Additional sequence information

        N-terminal 6xHis-SUMO tag.

    Specifications

    Our Abpromise guarantee covers the use of ab226231 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      Constituents: 50% Glycerol (glycerin, glycerine), Tris buffer

    General Info

    • Alternative names

      • Delta Drosophila like 3
      • Delta like 3 Drosophila
      • Delta like 3 homolog Drosophila
      • Delta like 3 protein
      • Delta like protein 3 precursor
      • Delta-like protein 3
      • Delta3
      • Dll3
      • DLL3_HUMAN
      • Drosophila Delta homolog 3
      • SCDO1
      • SCOD1
      • Spondylocostal dysostosis autosomal recessive
      see all

    • Function

      Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.

    • Involvement in disease

      Spondylocostal dysostosis 1

    • Sequence similarities

      Contains 1 DSL domain.
      Contains 6 EGF-like domains.

    • Domain

      The DSL domain is required for binding to the Notch receptor.

    • Post-translational
      modifications

      Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.

    • Cellular localization

      Membrane.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human DLL3 protein (Tagged) (ab226231)
      SDS-PAGE - Recombinant Human DLL3 protein (Tagged) (ab226231)

      (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab226231? Please let us know so that we can cite the reference in this datasheet.

    ab226231 has not yet been referenced specifically in any publications.

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