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Based on the descriptions, they are all Fc-fusions of DR5 protein. I'm trying to understand if they have a functional difference, and what the source of that difference may be.
Asked on Apr 15 2013
These proteins are all Fc-fusions of different fragments of DR5. Ab83547 contains amino acids 56-182, ab56519 contains amino acids 1-182, and ab109149 contains amino acids 52-212. Because of these different sequences, the functionality may vary among the proteins.
Ab56519 has not been tested for functionality, but the other two proteins have been shown to neutralize TRAIL activity, and we fully guarantee them to do so.
Answered on Apr 15 2013