Overview

  • Product name

    Recombinant Human DS-1 protein
  • Protein length

    Full length protein

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSLHKQKDG TEFKSIYSLD KLYPESQGSD TAWRVPNGAK QADSDIPLDR LTISYCRSSG PGGQNVNKVN SKAEVRFHLA TAEWIAEPVR QKIAITHKNK INRLGELILT SESSRYQFRN LADCLQKIRD MITEASQTPK EPTKEDVKLH RIRIENMNRE RLRQKRIHSA VKTSRRVDMD
    • Molecular weight

      23 kDa including tags
    • Amino acids

      30 to 206
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab137167 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Purity

    > 90 % SDS-PAGE.
    ab137167 was purified using conventional chromatography.
  • Form

    Liquid
  • Additional notes

    Previously labelled as ICT1.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 30% Glycerol, 1.17% Sodium chloride

General Info

  • Alternative names

    • Digestion substraction 1
    • DS-1
    • DS1
    • Ict1
    • ICT1_HUMAN
    • Immature colon carcinoma transcript 1
    • Immature colon carcinoma transcript 1 protein
    • mitochondrial
    • Peptidyl-tRNA hydrolase ICT1
    • Peptidyl-tRNA hydrolase ICT1, mitochondrial
    see all
  • Function

    Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.
  • Tissue specificity

    Down-regulated during the in vitro differentiation of HT29-D4 colon carcinoma cells.
  • Sequence similarities

    Belongs to the prokaryotic/mitochondrial release factor family. ICT1 subfamily.
  • Cellular localization

    Mitochondrion.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab137167 (3µg)

References

ab137167 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab137167.
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