Recombinant Human DSCAML1 protein (ab163552)

Our Abpromise guarantee covers the use of ab163552 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Alternative names
- Down syndrome cell adhesion molecule 2
- Down syndrome cell adhesion molecule like 1
- Down syndrome cell adhesion molecule like protein 1
- Down syndrome cell adhesion molecule-like protein 1
- DSCAM2
- DSCAML1
- DSCL1_HUMAN
see all
Function

Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to maintain mosaic spacing between AII amacrine cells.
Tissue specificity

Detected in heart, liver, pancreas, skeletal muscle, kidney and in brain, in particular in the amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra, thalamus and subthalamus.
Sequence similarities

Contains 6 fibronectin type-III domains.
Contains 10 Ig-like C2-type (immunoglobulin-like) domains.
Cellular localization

Cell membrane.
Target information above from: UniProt accession Q8TD84 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Human DSCAML1 protein (ab163552)

ab163552 on a 12.5% SDS-PAGE stained with Coomassie Blue.

ab163552 has not yet been referenced specifically in any publications.

Publishing research using ab163552? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"