Description

  • Product name

    Recombinant Human DUSP22 protein (denatured)
    See all DUSP22 proteins and peptides
  • Purity

    > 85 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSMGNGMNK ILPGLYIGNF KDARDAEQLS KNKVTHILSV HDSARPMLEG VKYLCIPAAD SPSQNLTRHF KESIKFIHEC RLRGESCLVH CLAGVSRSVT LVIAYIMTVT DFGWEDALHT VRAGRSCANP NVGFQRQLQE FEKHEVHQYR QWLKEEYGES PLQDAEEAKN ILAAPGILKF WAFLRRL
    • Predicted molecular weight

      23 kDa including tags
    • Amino acids

      1 to 184
    • Tags

      His tag N-Terminus
    • Additional sequence information

      NP_064570.
  • Description

    Recombinant Human DUSP22 protein

Specifications

Our Abpromise guarantee covers the use of ab180296 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.0
    Constituents: 0.32% Tris HCl, 2.4% Urea, 10% Glycerol

General Info

  • Alternative names

    • Dual specificity protein phosphatase 22
    • DUS22_HUMAN
    • Dusp22
    • JNK stimulatory phosphatase 1
    • JNK-stimulatory phosphatase-1
    • JSP 1
    • JSP-1
    • JSP1
    • LMW DSP2
    • LMW-DSP2
    • Low molecular weight dual specificity phosphatase 2
    • MAP kinase phosphatase x
    • Mitogen activated protein kinase phosphatase x
    • Mitogen-activated protein kinase phosphatase x
    • MKP-x
    • MKPX
    see all
  • Function

    Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK).
  • Tissue specificity

    Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.
  • Sequence similarities

    Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab180296 (3μg).

References

ab180296 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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