Recombinant Human DUSP26 protein (denatured) (ab171697)

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SDS-PAGE - Recombinant Human DUSP26 protein (denatured) (ab171697)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 85% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE

    Description

    • Product name

      Recombinant Human DUSP26 protein (denatured)

    • Purity

      > 85 % SDS-PAGE.

    • Expression system

      Escherichia coli

    • Accession

      Q9BV47

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MGSSHHHHHH SSGLVPRGSH MGSMCPGNWL WASMTFMARF SRSSSRSPVR TRGTLEEMPT VQHPFLNVFE LERLLYTGKT ACNHADEVWP GLYLGDQDMA NNRRELRRLG ITHVLNASHS RWRGTPEAYE GLGIRYLGVE AHDSPAFDMS IHFQTAADFI HRALSQPGGK ILVHCAVGVS RSATLVLAYL MLYHHLTLVE AIKKVKDHRG IIPNRGFLRQ LLALDRRLRQ GLEA

      • Predicted molecular weight

        26 kDa

      • Amino acids

        1 to 211

      • Tags

        His tag N-Terminus

    • Description

      Recombinant Human DUSP26 protein

    Specifications

    Our Abpromise guarantee covers the use of ab171697 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

      pH: 8.00
      Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol (glycerin, glycerine)

    General Info

    • Alternative names

      • DSP-4
      • Dual specificity phosphatase 26
      • Dual specificity phosphatase 26 (putative)
      • Dual specificity phosphatase SKRP3
      • Dual specificity protein phosphatase 26
      • DUS26_HUMAN
      • DUSP24
      • DUSP26
      • Hypothetical protein FLJ31142
      • LDP 4
      • LDP-4
      • Low molecular mass dual specificity phosphatase 4
      • Low-molecular-mass dual-specificity phosphatase 4
      • MAP kinase phosphatase 8
      • MGC1136
      • MGC2627
      • Mitogen activated protein kinase phosphatase 8
      • Mitogen-activated protein kinase phosphatase 8
      • MKP-8
      • MKP8
      • NATA1
      • NATA1 protein
      • Novel amplified gene in thyroid anaplastic cancer
      • SKRP3
      see all

    • Function

      Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).

    • Tissue specificity

      Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer.

    • Sequence similarities

      Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
      Contains 1 tyrosine-protein phosphatase domain.

    • Cellular localization

      Cytoplasm. Nucleus. Golgi apparatus.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human DUSP26 protein (denatured) (ab171697)
      SDS-PAGE - Recombinant Human DUSP26 protein (denatured) (ab171697)
      15% SDS-PAGE analysis of ab171697 (3 µg).

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab171697? Please let us know so that we can cite the reference in this datasheet.

    ab171697 has not yet been referenced specifically in any publications.

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