Recombinant Human p50 dynamitin protein (ab174453)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE, MS
Description
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Product name
Recombinant Human p50 dynamitin protein -
Purity
> 90 % SDS-PAGE.
ab174453 is purified by using conventional chromatography techniques. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MGSSHHHHHHSSGLVPRGSHMGSMADPKYADLPGIARNEPDVYETSDLPE DDQAEFDAFAQELEELTSTSVEHIIVNPNAAYDKFKDKRVGTKGLDFSDR IGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKIKT TVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGA LAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAA KVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALD LAVLDQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPI ASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLT QVQTTMRENLATVEGNFASIDERMKKLGK -
Predicted molecular weight
47 kDa including tags -
Amino acids
1 to 406 -
Tags
His tag N-Terminus -
Additional sequence information
NCBI Accession No.: NP_006391
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab174453 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
Mass Spectrometry
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Mass spectrometry
MALDI-TOF -
Form
Liquid -
Additional notes
Previously labelled as Dynamitin.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.32% Tris HCl, 20% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.02% DTT
General Info
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Alternative names
- 50 kD dynein associated polypeptide
- 50 kDa dynein associated polypeptide
- 50 kDa dynein-associated polypeptide
see all -
Function
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development. -
Sequence similarities
Belongs to the dynactin subunit 2 family. -
Cellular localization
Cytoplasm > cytoskeleton > centrosome. Membrane. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab174453 has not yet been referenced specifically in any publications.