Overview

  • Product name

    Recombinant Human Dynein axonemal intermediate chain protein
  • Protein length

    Full length protein

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Species

      Human
    • Sequence

      MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDS DLDRKRRETEALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDL GPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYS KETQTPLATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELT EEEKQQILHLEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDV QAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEP DGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVL WDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCS WSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTA CRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLW TTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTE VPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWVYDVGELAVPHNDE WTRFARTLVEIRANRADSEEEGTVELSA
    • Amino acids

      1 to 628
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab158299 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • Cytoplasmic dynein 1 intermediate chain 1
    • Cytoplasmic dynein intermediate chain 1
    • cytosolic
    • DC1I1_HUMAN
    • DH IC 1
    • DH IC-1
    • DH IC1
    • DNCI1
    • DNCIC1
    • Dync1i1
    • Dynein cytoplasmic 1 intermediate chain 1
    • Dynein intermediate chain 1
    • Dynein intermediate chain 1, cytosolic
    • Dynein, cytoplasmic, intermediate polypeptide 1
    see all
  • Function

    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
  • Sequence similarities

    Belongs to the dynein intermediate chain family.
    Contains 7 WD repeats.
  • Cellular localization

    Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.
  • Information by UniProt

Images

  • ab158299 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab158299 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab158299.
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