Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSQTLKDTT SSSSADSTIM DIQVPTRAPD AVYTELQPTS PTPTWPADET PQPQTQTQQL EGTDGPLVTD PETHKSTKAA HPTDDTTTLS ERPSPSTDVQ TDPQTLKPSG FHEDDPFFYD EHTLRKR
    • Molecular weight

      16 kDa including tags
    • Amino acids

      22 to 145
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab140573 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Purity

    > 95 % SDS-PAGE.
    ab140573 was purified using conventional chromatography techniques.
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

General Info

  • Alternative names

    • Dysad
    • Dysadherin
    • FXYD 5
    • FXYD domain containing ion transport regulator 5
    • FXYD domain-containing ion transport regulator 5
    • Fxyd5
    • FXYD5_HUMAN
    • FXYD5RIC
    • HSPC 113
    • HSPC113
    • IWU 1
    • IWU1
    • KCT 1
    • KCT1
    • Keratinocytes associated transmembrane protein 1
    • OIT 2
    • OIT2
    • PRO 6241
    • PRO6241
    • RIC
    see all
  • Function

    Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis.
  • Sequence similarities

    Belongs to the FXYD family.
  • Post-translational
    modifications

    Glycosylated.
  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • 15% SDS PAGE analysis of ab140573 (3 µg).

References

ab140573 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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