Overview

Description

  • Nature

    Recombinant
  • Source

    Baculovirus infected insect cells
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      ADPMDCQENE YWDQWGRCVT CQRCGPGQEL SKDCGYGEGG DAYCTACPPR RYKSSWGHHR CQSCITCAVI NRVQKVNCTA TSNAVCGDCL PRFYRKTRIG GLQDQECIPC TKQTPTSEVQ CAFQLSLVEA DAPTVPPQEA TLEPKSCDKT HTCPPCPAPE LLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSHEDPEV KFNWYVDGVE VHNAKTKPRE EQYNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKALPAPIE KTISKAKGQP REPQVYTLPP SRDELTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSKLTVD KSRWQQGNVF SCSVMHEALH NHYTQKSLSL SPGKHHHHHH
    • Molecular weight

      43 kDa including tags
    • Amino acids

      1 to 139
    • Tags

      His tag C-Terminus
    • Additional sequence information

      Extracellular domain with hIgG-His-tag at C terminal.

Specifications

Our Abpromise guarantee covers the use of ab219489 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Endotoxin level

    < 1.000 Eu/µg
  • Purity

    > 90 % SDS-PAGE.
    Purified by using conventional chromatography techniques.
  • Form

    Liquid
  • Additional notes

     This product was previously labelled as EDA2R

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: PBS, 20% Glycerol, 0.02% DTT

General Info

  • Alternative names

    • 9430060M22Rik
    • Ectodysplasin A2 isoform receptor
    • Ectodysplasin A2 receptor
    • EDA A2R
    • EDA-A2 receptor
    • EDA2R
    • EDAA2R
    • MGC124099
    • OTTMUSP00000019574
    • OTTMUSP00000019575
    • RP23-188N15.1
    • TNFRSF27
    • TNR27_HUMAN
    • Tumor necrosis factor receptor superfamily member 27
    • Tumor necrosis factor receptor superfamily member XEDAR
    • X linked ectodysplasin A2 receptor
    • X linked ectodysplasin receptor
    • X-linked ectodysplasin-A2 receptor
    • XEDAR
    see all
  • Function

    Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6.
  • Sequence similarities

    Contains 3 TNFR-Cys repeats.
  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • 15% SDS-PAGE - Recombinant Human EDA2R/XEDAR protein (ab219489) at 3 μg.

References

ab219489 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab219489.
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