Recombinant Human EDC3 protein (ab132637)

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Description

  • Product name

    Recombinant Human EDC3 protein

  • Expression system

    Wheat germ

  • Accession

    Q96F86

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MATDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVP EVTFRAGDITELKILEIPGPGDNQHFGDLHQTELGPSGAGCQVGINQNGT GKFVKKPASSSSAPQNIPKRTDVKSQDVAVSPQQQQCSKSYVDRHMESLS QSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEEIP DTDFDFEGNLALFDKAAVFEEIDTYERRSGTRSRGIPNERPTRYRHDENI LESEPIVYRRIIVPHNVSKEFCTDSGLVVPSISYELHKKLLSVAEKHGLT LERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPTVALLCGPHVKGAQG ISCGRHLANHDVQVILFLPNFVKMLESITNELSLFSKTQGQQVSSLKDLP TSPVDLVINCLDCPENVFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEVE QGIDAKWSLALGLPLPLGEHAGRIYLCDIGIPQQVFQEVGINYHSPFGCK FVIPLHSA

    • Predicted molecular weight

      82 kDa including tags

    • Amino acids

      1 to 508

Specifications

Our Abpromise guarantee covers the use of ab132637 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Form

    Liquid

  • Additional notes

    This protein is best used within three months from the date of receipt.

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • EDC 3
    • edc3
    • EDC3_HUMAN
    • Enhancer of mRNA decapping 3 homolog
    • enhancer of mRNA decapping 3 homolog (S. cerevisiae)
    • Enhancer of mRNA decapping 3, S. cerevisiae, homolog of
    • Enhancer of mRNA decapping protein 3
    • Enhancer of mRNA-decapping protein 3
    • FLJ21128
    • FLJ31777
    • hYjeF_N2
    • hYjeF_N2-15q23
    • LSM 16
    • LSM16
    • LSM16 homolog
    • LSM16 homolog (EDC3 S. cerevisiae)
    • LSM16 homolog (EDC3, S. cerevisiae)
    • YJDC
    • YjeF domain containing
    • YjeF domain containing protein
    • YjeF domain containing protein 1
    • YjeF domain-containing protein 1
    • YjeF N-terminal domain-containing protein 2
    • YjeF_N2
    • YJEFN2
    see all

  • Function

    Binds single-stranded RNA. In the process of mRNA degradation, may play a role in mRNA decapping. May play a role in spermiogenesis and oogenesis.

  • Tissue specificity

    Expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level). Also expressed in brain and mammary gland.

  • Sequence similarities

    Belongs to the EDC3 family.
    Contains 1 DFDF domain.
    Contains 1 YjeF N-terminal domain.

  • Domain

    The DFDF domain is unstructured by itself. It assumes a helical fold upon interaction with DDX6.

  • Cellular localization

    Cytoplasm > P-body. Processing bodies.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human EDC3 protein (ab132637)
    SDS-PAGE - Recombinant Human EDC3 protein (ab132637)
    12.5% SDS-PAGE analysis of ab132637 stained with Coomassie Blue.

References

ab132637 has not yet been referenced specifically in any publications.

Publishing research using ab132637? Please let us know so that we can cite the reference in this datasheet.

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