Recombinant Human EFHD2/SWS1 protein (ab132296)

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SDS-PAGE - Recombinant Human EFHD2/SWS1 protein (ab132296)

    Key features and details

    • Expression system: Wheat germ
    • Suitable for: ELISA, SDS-PAGE, WB

    Description

    • Product name

      Recombinant Human EFHD2/SWS1 protein

    • Expression system

      Wheat germ

    • Accession

      Q96C19

    • Protein length

      Full length protein

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MATDELATKLSRRLQMEGEGGGETPEQPGLNGAAAAAAGAPDEAAEALGS ADCELSAKLLRRADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKM FKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSF REFLLIFRKAAAGELQEDSGLCVLARLSEIDVSSEGVKGAKSFFEAKVQA INVSSRFEEEIKAEQEERKKQAEEMKQRKAAFKELQSTFK

      • Predicted molecular weight

        53 kDa including tags

      • Amino acids

        1 to 240

    Specifications

    Our Abpromise guarantee covers the use of ab132296 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      ELISA

      SDS-PAGE

      Western blot

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    General Info

    • Alternative names

      • EF hand domain containing protein 2
      • EF hand domain family, member D2
      • EF-hand domain-containing protein D2
      • EFHD 2
      • EFHD2
      • EFHD2_HUMAN
      • RP3-467K16.3
      • Swiprosin 1
      • Swiprosin-1
      • SWS1
      see all

    • Function

      May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.

    • Tissue specificity

      Found in lymphocytes; preferentially expressed in CD8+ cells.

    • Sequence similarities

      Contains 2 EF-hand domains.

    • Cellular localization

      Membrane raft. In immature B-cell line WEHI231.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human EFHD2/SWS1 protein (ab132296)
      SDS-PAGE - Recombinant Human EFHD2/SWS1 protein (ab132296)
      12.5% SDS-PAGE stained with Coomassie Blue showing ab132296.

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab132296? Please let us know so that we can cite the reference in this datasheet.

    ab132296 has not yet been referenced specifically in any publications.

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