Recombinant Human EFHD2/SWS1 protein (ab132296)

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Description

  • Product name

    Recombinant Human EFHD2/SWS1 protein
    See all EFHD2/SWS1 proteins and peptides

  • Expression system

    Wheat germ

  • Accession

    Q96C19

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MATDELATKLSRRLQMEGEGGGETPEQPGLNGAAAAAAGAPDEAAEALGS ADCELSAKLLRRADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKM FKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSF REFLLIFRKAAAGELQEDSGLCVLARLSEIDVSSEGVKGAKSFFEAKVQA INVSSRFEEEIKAEQEERKKQAEEMKQRKAAFKELQSTFK

    • Predicted molecular weight

      53 kDa including tags

    • Amino acids

      1 to 240

Specifications

Our Abpromise guarantee covers the use of ab132296 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form

    Liquid

  • Additional notes

    This protein is best used within three months from the date of receipt.

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • EF hand domain containing protein 2
    • EF hand domain family, member D2
    • EF-hand domain-containing protein D2
    • EFHD 2
    • EFHD2
    • EFHD2_HUMAN
    • RP3-467K16.3
    • Swiprosin 1
    • Swiprosin-1
    • SWS1
    see all

  • Function

    May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.

  • Tissue specificity

    Found in lymphocytes; preferentially expressed in CD8+ cells.

  • Sequence similarities

    Contains 2 EF-hand domains.

  • Cellular localization

    Membrane raft. In immature B-cell line WEHI231.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human EFHD2/SWS1 protein (ab132296)
    SDS-PAGE - Recombinant Human EFHD2/SWS1 protein (ab132296)
    12.5% SDS-PAGE stained with Coomassie Blue showing ab132296.

References

ab132296 has not yet been referenced specifically in any publications.

Publishing research using ab132296? Please let us know so that we can cite the reference in this datasheet.

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