Recombinant Human EIF2S2 protein (ab160247)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MSGDEMIFDPTMSKKKKKKKKPFMLDEEGDTQTEETQPSETKEVEPEPTE DKDLEADEEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFDIDEAEEGVKD LKIESDVQEPTEPEDDLDIMLGNKKKKKKNVKFPDEDEILEKDEALEDED NKKDDGISFSNQTGPAWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKR KFVMKPPQVVRVGTKKTSFVNFTDICKLLHRQPKHLLAFLLAELGTSGSI DGNNQLVIKGRFQQKQIENVLRRYIKEYVTCHTCRSPDTILQKDTRLYFL QCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN
    • Amino acids
      1 to 333
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab160247 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • DKFZp686L18198
    • eIF 2 beta
    • eIF-2-beta
    • EIF2
    • EIF2B
    • EIF2beta
    • EIF2S2
    • Eukaryotic initiation factor 2 beta
    • eukaryotic initiation factor 2-beta
    • Eukaryotic translation initiation factor 2 beta
    • Eukaryotic translation initiation factor 2 subunit 2
    • Eukaryotic translation initiation factor 2 subunit 2 beta
    • Eukaryotic translation initiation factor 2 subunit 2 beta 38kDa
    • Eukaryotic translation initiation factor 2 subunit beta
    • eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
    • IF2B_HUMAN
    • MGC8508
    • PPP1R67
    • protein phosphatase 1, regulatory subunit 67
    see all
  • Function
    eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
  • Sequence similarities
    Belongs to the eIF-2-beta/eIF-5 family.
  • Information by UniProt

Images

  • ab160247 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab160247 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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