Description

  • Product name

    Recombinant Human Endofin protein
  • Purity

    > 95 % Purified via His tag.
    Purity is >95% by SDS-PAGE.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      28 kDa
    • Amino acids

      369 to 623
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127797 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Additional notes

    Previously labelled as ZFYVE16. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names

    • AI035632
    • B130024H06Rik
    • B130031L15
    • DKFZp686E13162
    • Endofin
    • Endosomal associated FYVE domain protein
    • Endosome associated FYVE domain protein
    • Endosome-associated FYVE domain protein
    • KIAA0305
    • KIAA0305;
    • mKIAA0305
    • OTTMUSP00000029589
    • RGD1564784
    • ZFY16_HUMAN
    • ZFYVE16
    • Zinc finger FYVE domain containing protein 16
    • Zinc finger FYVE domain-containing protein 16
    • Zinc finger, FYVE domain containing 16
    see all
  • Function

    May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.
  • Tissue specificity

    Widely expressed. Highly expressed in kidney, placenta and lung. Expressed at intermediate level in heart, brain, skeletal muscle, spleen and liver. Weakly expressed in colon, thymus and peripheral blood lymphocytes.
  • Sequence similarities

    Contains 1 FYVE-type zinc finger.
  • Domain

    The FYVE-type zinc finger is necessary and sufficient for its localization into early endosomes and mediates the association with PI3P.
  • Cellular localization

    Cytoplasm. Early endosome membrane. Localized to early endosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate.
  • Information by UniProt

References

ab127797 has not yet been referenced specifically in any publications.

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