Recombinant Human ENTPD5 protein (ab132837)
- Datasheet
- References
- Protocols
Description
-
Product name
Recombinant Human ENTPD5 protein
See all ENTPD5 proteins and peptides -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
-
Species
Human -
Sequence
MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG IMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVKPGLSAFVDQPKQG AETVQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFEVKE IFRKSPFLVPKGSVSIMDGSDEGILAWVTVNFLTGQLHGHRQETVGTLDL GGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAA RLATLGALETEGTDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQEGEVGF EPCYAEVLRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKGGIL KVEDFERKAREVCDNLENFTSGSPFLCMDLSYITALLKDGFGFADSTVLQ HIISWVN -
Predicted molecular weight
70 kDa including tags -
Amino acids
1 to 407
-
Associated products
-
Related Products
Specifications
Our Abpromise guarantee covers the use of ab132837 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
ELISA
SDS-PAGE
Western blot
-
Form
Liquid -
Additional notes
-
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
-
Alternative names
- CD39 like 4
- AI196558
- AI987697
see all -
Function
Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling. -
Tissue specificity
Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues. -
Pathway
Protein modification; protein glycosylation. -
Sequence similarities
Belongs to the GDA1/CD39 NTPase family. -
Post-translational
modificationsN-glycosylated; high-mannose type. -
Cellular localization
Endoplasmic reticulum lumen. - Information by UniProt
Images
-
SDS-PAGE - Recombinant Human ENTPD5 protein (ab132837)12.5% SDS-PAGE analysis of ab132837 stained with Coomassie Blue.
Datasheets and documents
References
ab132837 has not yet been referenced specifically in any publications.
