Description

  • Product name

    Recombinant Human EPCR/CD201 protein (denatured)
    See all EPCR/CD201 proteins and peptides
  • Purity

    > 80 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHHSSGLVPRGSHMGSSQDASDGLQRLHMLQISYFRDPYHVWY QGNASLGGHLTHVLEGPDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFH GLVRLVHQERTLAFPLTIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFR PERALWQADTQVTSGVVTFTLQQLNAYNRTRYELREFLEDTCVQYVQKHI SAENTKGSQTSRSYTS
    • Predicted molecular weight

      24 kDa including tags
    • Amino acids

      18 to 210
    • Tags

      His tag N-Terminus
    • Additional sequence information

      Extracellular domain. Protein accession number; NP_006395
  • Description

    Recombinant Human EPCR/CD201 protein

Specifications

Our Abpromise guarantee covers the use of ab180310 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8
    Constituents: 0.32% Tris HCl, 10% Glycerol, 2.4% Urea

General Info

  • Alternative names

    • Activated protein C receptor
    • APC receptor
    • APCR
    • bA42O4.2
    • CCCA
    • CCD41
    • CD201
    • CD201 antigen
    • cell cycle, centrosome-associated protein
    • Cell cycle, centrosome-associated protein
    • centrocyclin
    • Endothelial cell protein C receptor
    • Endothelial protein C receptor
    • EPCR
    • EPCR_HUMAN
    • MGC23024
    • PROCR
    • Protein C receptor, endothelial
    see all
  • Function

    Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
  • Tissue specificity

    Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney.
  • Post-translational
    modifications

    N-glycosylated.
    A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form.
  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab180310 (3 µg).

References

ab180310 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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