Product nameRecombinant human Eph receptor A3 protein
See all Eph receptor A3 proteins and peptides
Protein lengthProtein fragment
SourceBaculovirus infected Sf9 cells
Amino Acid Sequence
Amino acids571 to 983
Our Abpromise guarantee covers the use of ab84576 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activitySpecific activity of Eph receptor A3 was determined to be 102 nmol/min/mg as per activity assay protocol.
Purity> 90 % SDS-PAGE.
Purity was determined to be >90% by densitometry.
ab204877 (Poly (4:1 Glu, Tyr) peptide) can be utilized as a substrate for assessing kinase activity
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- EC 184.108.40.206
FunctionReceptor for members of the ephrin-A family. Binds to ephrin-A2, -A3, -A4 and -A5. Could play a role in lymphoid function.
Tissue specificityWidely expressed. Highest level in placenta.
Involvement in diseaseDefects in EPHA3 may be a cause of colorectal cancer (CRC) [MIM:114500].
Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
Contains 2 fibronectin type-III domains.
Contains 1 protein kinase domain.
Contains 1 SAM (sterile alpha motif) domain.
Cellular localizationSecreted and Cell membrane.
- Information by UniProt
ab84576 has not yet been referenced specifically in any publications.