Recombinant Human Epoxide hydrolase protein (denatured) (ab177622)

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SDS-PAGE - Recombinant Human Epoxide hydrolase protein (denatured) (ab177622)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 90% SDS-PAGE
    • Tags: T7 tag N-Terminus
    • Suitable for: SDS-PAGE

    Description

    • Product name

      Recombinant Human Epoxide hydrolase protein (denatured)
      See all Epoxide hydrolase proteins and peptides

    • Purity

      > 90 % SDS-PAGE.

    • Expression system

      Escherichia coli

    • Accession

      P07099

    • Protein length

      Protein fragment

    • Animal free

      No

    • Nature

      Recombinant

      • Species

        Human

      • Sequence

        MASMTGGQQM GRGSHMRDKE ETLPLEDGWW GPGTRSAARE DDSIRPFKVE TSDEEIHDLH QRIDKFRFTP PLEDSCFHYG FNSNYLKKVI SYWRNEFDWK KQVEILNRYP HFKTKIEGLD IHFIHVKPPQ LPAGHTPKPL LMVHGWPGSF YEFYKIIPLL TDPKNHGLSD EHVFEVICPS IPGYGFSEAS SKKGFNSVAT ARIFYKLMLR LGFQEFYIQG GDWGSLICTN MAQLVPSHVK GLHLNMALVL SNFSTLTLLL GQRFGRFLGL TERDVELLYP VKEKVFYSLM RESGYMHIQC TKPDTVGSAL NDSPVGLAAY ILEKFSTWTN TEFRYLEDGG LERKFSLDDL LTNVMLYWTT GTIISSQRFY KENLGQGWMT QKHERMKVYV PTGFSAFPFE LLHTPEKWVR FKYPKLISYS YMVRGGHFAA FEEPELLAQD IRKFLSVLER Q

      • Predicted molecular weight

        52 kDa including tags

      • Amino acids

        21 to 455

      • Tags

        T7 tag N-Terminus

    Specifications

    Our Abpromise guarantee covers the use of ab177622 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituents: 0.32% Tris HCl, 2.4% Urea, 10% Glycerol (glycerin, glycerine)

    General Info

    • Alternative names

      • EPHX
      • EPHX 1
      • Ephx1
      • EPOX
      • Epoxide hydratase
      • Epoxide hydrolase 1
      • Epoxide hydrolase 1 microsomal (xenobiotic)
      • Epoxide hydroxylase 1
      • Epoxide hydroxylase 1 microsomal (xenobiotic)
      • HYEP_HUMAN
      • HYL1
      • MEH
      • Microsomal epoxide hydrolase
      see all

    • Function

      Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.

    • Tissue specificity

      Found in liver.

    • Involvement in disease

      Note=In some populations, the high activity haplotype tyr113/his139 is overrepresented among women suffering from pregnancy-induced hypertension (pre-eclampsia) when compared with healthy controls.
      Defects in EPHX1 are a cause of familial hypercholanemia (FHCA) [MIM:607748]. FHCA is a disorder characterized by elevated serum bile acid concentrations, itching, and fat malabsorption.

    • Sequence similarities

      Belongs to the peptidase S33 family.

    • Cellular localization

      Microsome membrane. Endoplasmic reticulum membrane.
    • Information by UniProt

    Images

    • SDS-PAGE - Recombinant Human Epoxide hydrolase protein (denatured) (ab177622)
      SDS-PAGE - Recombinant Human Epoxide hydrolase protein (denatured) (ab177622)

      15% SDS-PAGE analysis of ab177622 (3µg)

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab177622? Please let us know so that we can cite the reference in this datasheet.

    ab177622 has not yet been referenced specifically in any publications.

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