Recombinant Human Epsin 2 protein (ab161471)

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Description

  • Product name

    Recombinant Human Epsin 2 protein

  • Expression system

    Wheat germ

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNV VAFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENI F

    • Amino acids

      1 to 101

    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161471 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid

  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • EHB21
    • EPN 2
    • Epn2
    • EPN2_HUMAN
    • EPS 15 interacting protein 2
    • EPS-15-interacting protein 2
    • Eps15 binding protein
    • Epsin 2
    • Epsin-2
    • Epsin2
    • KIAA1065
    • OTTHUMP00000065808
    • OTTHUMP00000065809
    • OTTHUMP00000065810
    • OTTHUMP00000065811
    • OTTHUMP00000065889
    see all

  • Function

    Plays a role in the formation of clathrin-coated invaginations and endocytosis.

  • Tissue specificity

    Highest expression is found in brain. Detected at lower levels in lung and liver.

  • Sequence similarities

    Belongs to the epsin family.
    Contains 1 ENTH (epsin N-terminal homology) domain.
    Contains 2 UIM (ubiquitin-interacting motif) repeats.

  • Domain

    The NPF repeat domain is involved in EPS15 binding.
    The DPW repeat domain is involved in AP-2 and clathrin binding.

  • Post-translational
    modifications

    Ubiquitinated.

  • Cellular localization

    Cytoplasm. Cytoplasmic vesicle > clathrin-coated vesicle. In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Epsin 2 protein (ab161471)
    SDS-PAGE - Recombinant Human Epsin 2 protein (ab161471)
    ab161471 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161471 has not yet been referenced specifically in any publications.

Publishing research using ab161471? Please let us know so that we can cite the reference in this datasheet.

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