The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
EPS 15 interacting protein 2
EPS-15-interacting protein 2
Eps15 binding protein
Plays a role in the formation of clathrin-coated invaginations and endocytosis.
Highest expression is found in brain. Detected at lower levels in lung and liver.
Belongs to the epsin family. Contains 1 ENTH (epsin N-terminal homology) domain. Contains 2 UIM (ubiquitin-interacting motif) repeats.
The NPF repeat domain is involved in EPS15 binding. The DPW repeat domain is involved in AP-2 and clathrin binding.
Cytoplasm. Cytoplasmic vesicle > clathrin-coated vesicle. In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.